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CD28 抗体

This anti-CD28 antibody is a 仓鼠 单克隆 antibody detecting CD28 in FACS. Suitable for 小鼠.
产品编号 ABIN135184
发货至: 中国

Quick Overview for CD28 抗体 (ABIN135184)

抗原

See all CD28 抗体
CD28

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD28 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

37-51
  • 特异性

    Mouse CD28, Mr 40 kDa

    产品特性

    Hamster Anti-Mouse CD28-LE/AF

    内毒素水平

    Low endotoxin

    免疫原

    C57BL/6N mouse T cell lymphoma EL-4 cell line

    亚型

    IgG
  • 应用备注

    • Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Stim - Reported in literature , Activ - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    说明

    In vitro costimulation of T cells and NK cells

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    0.5 mg of purified immunoglobulin in 1.0 mL of PBS

    储存液

    Azide free

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    -20 °C

    储存方法

    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • 抗原

    CD28

    别名

    CD28

    背景

    CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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